Penn State Opens as a Slim Betting Favorite Over Michigan State

With Michigan State coming off one of the worse beatdowns of the college football season in a 56-7 loss to Ohio State, it’ll be interesting to see just what team comes out against Penn State.

Circa Sports has set Penn State as a one-point favorite in a 3:30 p.m. game at Spartan Stadium in East Lansing, Michigan on Saturday. The over/under has been set at 53.5 points between two teams that excel in contrasting areas on offensive and defense.

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— Circa Sports (@CircaSports) November 21, 2021

DraftKings Sportsbook is higher on Michigan State than Penn State, setting the Spartans as a 1.5-point favorite. A bet against the spread for PSU holds -120 odds while the same bet for MSU holds +100 odds. The over/under is set at 53 points, with both options holding -110 odds.

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Michigan State is 7-3-1 against the spread this season, failing to cover in losses to Ohio State and Purdue over the past three weeks. Penn State is 7-4 against the spread, failing to cover in three of four losses this season.

Penn State is 16-17-1 against Michigan State all-time, the first meeting coming in 1914. PSU has won two of the last three meetings, including a 39-24 win at Beaver Stadium last year, but MSU is 5-3 dating back to 2010.